This is one of my favorite novels by Jodi Picoult. The story of Anna and Kate is certainly worthy of book clubs discussions. I often found myself upset with their parents in the book until I looked at my own two children and wondered what I might do myself if I were in the same situation. That is what Picoult's books always do for me - they draw me into the story and make me think about how I might choose if I were forced to do so. I love Picoult's writing style. This is one of her best novels to date.

Although this hasn't changed any of my political views about IVF or stem cell research, I enjoyed the story overall. It was a good tear-jerker and an easy read. It also made for good group discussion within my book club.

I could not put this book down. Jodi Picoult has a unique way of writing that draws you into the story. You see the story as it plays out through the various eyes of the participants. My only disappointment was that it had to end. There was so much more that could have been and should have been talked about and characters heard from.

This book was one of the best discussion books we have read in our Four years existence. It is the first book I agree should have been our book of the year. This book takes you through every emotion. It is educating and has several debatable issues that can keep your book club discussion going forever. Can you sacrifice one child for another? Do we realize what we are doing? Do we support stem cell research? When is enough a enough? These are just a few questions to discuss in this well written touching story. Please have a box of Kleenex it is a tearjerker.

JOdi Picoult manages to tackle a topical situation with aplomb. How one child's illness overshadows the needs of the other family members. A riveting sorrowful story that is excellecent for book club discussions. We had 40 attendees for a group and ALL enjoyed this book even if they found the subject matter painful and uncomfortable at times.

This book is a quick read that both saddens and uplifts the reader. There are many issues that the story relates that make for wonderful discussion topics.

The discussion was inciteful and as was obvious by the majority of those who participated

explores the ethics and complexities of genetics and social engineering as a younger daughter sues her parents for medical emancipation from being her older sister's donor. Great book for discussion groups. Explores both sides of the issues with heartwrenching story.

Jodi Picoult knows how to tug the heart strings-minus the sap you would think the storyline calls for. Told in rotating first person, thus getting the respective characters subjective thoughts of events, My Sister's Keeper brings much to discuss for groups. The family dynamic- or in this case, dysfunction- designer babies, genetics, loving unconditionally, sacrifice, and where exactly do lines cross.

Our discussion followed the expected course, pondering stem cell research, cord vs embyonic, breakthroughs since 2004. Whether we liked Sara, what Kate might have said to Anna, whether any 13 year olds can contact lawyers so easily, where are the pawn shops and are they in safe neighborhoods, why did it have to end the way it did..but I sensed that this book club is moving beyond the easy read, and that we are most enthralled with a more thoughtful, well written account of an issue, and that the good story with some humor is fine, but not worth discussion. Several of us did go on to read other Picoult works..but a few were just plain disappointed with the easy read. New dynamic..we have our first man joining...

This book was my first book of Jodi Picoult's. I have now read every one of her books and am in the middle of her latest, Nineteen Minutes. Jodi Picoult has a great style of writing and My Sister's Keeper is a great story of a family struggling with what is right and wrong. I recommend this book to everyone and hope you love it as much as I did!

Jodi Picoult can grab your attention from the opening page. This story is so true to life, and working in the transplant field, it has caused some very heart wrenching discussions in our office....I love the unexpected twists and turns in Picoult's books!

This book evoked the most interesting discussions and feelings among the members.

This was one of the most emotionally gripping books I have ever read. The characters are amazingly written and the story is riveting from the first page. It really is a must read.

I found this book entailed such an emotional rollercoaster. In this book the reader finds him/herself questioning the validity of the decisions being made. It is almost imposible to make a judgment, impossible almost to take sides.

The ending was the most painful of all. When I read it, I could not help but cry. It deeply touched me, as a parent and as a human being.

This is one book you would want to share, to talk with people about. Is it right? Is it wrong? When is enough enough? What would you do? Could you really do what you said you would, should you be in those shoes?

This is one thick book but very fast to read, because it's so un-put-down-able!

The author is very skilled in writing the story from so many viewpoints. Honestly it's the most I have seen. In some scenes, the scene continues but the first person changes from one to the another, and then it carries on to the next, like a well edited cinematography.

Don't want to sound smug, but I do somehow imagine the ending as it. Because, truly, that is the closest to a happy ending as can be.

This was a great book for book club. Whether you liked the book or not there was plenty to talk about.

Being a mom, this book really made me think about how far I would go to help my own children.

This book kept me interested and I found the author's style quite understadedly elegant.

Good topic for discussion

Our next book is Splendid Solution by Jeffrey Kluger

Due to the controversial nature of the story, it leaves you with much to discuss. It tears you between understanding the reasons for the events, and the moral, ethical, and emotional reasons for their discontinuance. There is so much to talk about with this one. As a Mother of 3 myself, it truly opened my eyes to things I never would have thought of if put into this Mother's situation.

This Picoult book will keep you reading and questioning all the way through the book. What is Anna's REAL reason that she doesn't want to donate a kidney to her critically ill older sister, Kate? How is it that the son of a Fire Captain is a pyromaniac? Will Anna's Mom, Sara, ever realize that she is "using" her younger daughter at the cost of her whole family? What the heck is Campbell's medical reason for his dog Judge -- a service dog? The ending will really throw readers for a loop, but in the end a "happy" family does remain.

The book was a bit hard for me to get into at first, as it wasn't exactly "fun" reading, but kind of sad....but as the book went on further, it completely enticed me in. Very interesting ending! (But still sad!)

Slow to catch on at first. Different voice per chapter was confusing at first, but necessary looking back. Book made me cry and then made me mad at author. Very thought provoking and compelling.

I could not put it down. The book was an easy read with many emotions and real life situations. The ending made me angry, but then so does life sometimes.

Excellent book. Someone had warned me that there would be a surprise ending, but it didn't prevent me from being surprised anyway. It was a true tear-jerker. I especially liked the fact that each chapter was written from another character's perspective. It helped "fill in the blanks", so to speak. If written from only one person's perspective, the book's subject matter might have appeared more black-and-white than it really was.

This was our favorite book club picks out in the past year. This author has a way of capturing your heart and mind.
It is highly recommended reading for everyone.

Excellent read!!! Funny in places, sad in places, heart-wrenching--really well- written. Expect a great discussion to follow.

Great book! Thought provoking and multi layered.

This book offered a lot of ethical questions to ponder and discuss. Really a page turner.

This is the second book we've read by this author, so we had an idea going into it what her style was. But I feel this book was monumentally better the other one we read (The Tenth Circle). I thought it was extremely well-written, with all the characters fully developed. You finish this book feeling like this family are your neighbors! And I thought this novel was such an excellent choice for discussion, as there were no easy answers to the conflicts the characters faced. As we are all mothers in our book club, this story especially hit home for us. The question "What would you do in this situation?" was always coming up. I would highly recommend this book for a discussion group, and just to read.

I found that this book had me changing my opinion as the story enfolded. I found that I had much empathy for Sara, as it must be the worst thing in the world to know that your child is going to die and I think you would do anything for that child to live. But then you think of how Anna must feel......The book really makes you think on both sides of the story. And what a twist at the end....quite upsetting. Would be an excellent book for book club discussions as I would anticipate many heated debates.

The book covered a very difficult subject. Many times during my reading I was upset by the Mother's actions. I felt badly for the whole family. One child was being saved but the rest were being lost. Jodi does a great job with redeeming some of her characters by the end of the book. The ending had me sobbing.

My grandson has leukemia so this was tough for me. I found the mother in the story totally unlikable. My daughter has knocked herself out to keep the other children in her family feeling secure and happy in their lives. Granted she has parents who are happy to help out, but I found the hardships of the healthy children in the novel to be excessive. Mary Kay

This book was a good book to discuss as to the moral issue of having a child so another child could live. It had a lot of various other issues included to make it a very interesting book to read and to discuss.

have not read

Very interesting character study!

There are so many choices made by the characters that create great discussion topics. A real tearjerker!

I will be the first to admit that I thought the premise was morbid. I would have missed out on a fabulous read if I had gone with my first instinct. If only I could erase my memory to read it again with the same eargerness and need-to-know that I had the first time....

This book is a real tear jerker. There are lots of topics included that make for a good discussion.

This book poses so many questions...and the discussions can just go round and round. What would you do to save your child? Will anyone who is not in that situation ever be able to honestly answer?

I loved this book. I know to some it is sad and depressing, but I thought it was really well researched and very insightful on the whole cancer situation.
I love how Jodi took this from a child's point of view and from the way the legal system looks at things, not so much from the way the cancer patient. It certainly changed my mind about stem cell research and the way people are being "engineered" for that sort of thing. It is sad, but I really loved it.

Could not put down this book! The relationship between the two girls and then their relationship with their parents allowed a lot of family dynamics discussion. Also an ethical discussion on having a child to save the child you already have. Some deep issues. A very moving story. Disccusion about how the two girls feel so much responsibility for each other. Also, each have mature insights that are beyond their years.

I thought the book was great, the writting style was above awesome. The story and characters feel very really. The author did a great job of bringing even small characters to life.

with the exception of her made for television ending, picoult manages to honestly examine the lives of five members of a family who are all dying from the same disease but differently. mostly well written.

I selected this book because of the controversial issues addressed in the book. The book really capitivated my attention and I did not want it to end! I would recommend this book for any book club!

I loved this book. It was a definite page turner. I liked the way the writing was done in the diferent characters voice. It is very moving to read what a family with a child with cancer can go through. Great story.

The title intrigued me, got my attention, not exactly what I expected, needed something to read..., then I was involved in the dilemma that this book presents, did not realize its also a movie,(I'm curious now to see how its played out). I thoroughly enjoyed the characters, just when you think what the inevitable will be , it changes, heart wrenching, soul searching, thought provoking dilemmas...insight to life values, what's important. The characters are great....

Made me think. What would i do if I were the parent? How would I feel if I were either of the children involved?

Reading this book had me asking some questions about morals. About harvesting children. About family loyalty. The story is a fight about life and freedom for 2 young girls. One dieing and the other one meant to be used to cure her sister.

This story is told from everyone in the story's viewpoint. It really makes you think about each person's situation and their feelings about it and leaves to wonder what you would do in that situation. You have to sympathize with all of them. Read, even if you see the movie, I haven't seen it yet, but I hear the ending is not the same!

Thought it was very well written. I enjoy all of Ms Picoult's books, each has their own morality issue and makes you wonder, if happened to you, what stance you would take on these issues. It's been a few years since I've read this, but I recall it was very hard to put this book down, I enjoyed it.

This is a thought provoking book- makes you think about what you would do as a mother faced with such horrible circumstances.

This was too sad for me, since I already deal with these types of situations in my daily job. I didin't enjoy reading it, although she writes very well. I don't think I would read another of hers. I prefer something that takes me away from my daily work

I thought the book was very thought provoking. Many interesting twists. I would read again. I wish it could have been a happier story.

the book was good it made me wonder how i would've handled the situation.

A gripping page turner. I couldn't put this book down. I never saw the ending coming!

This was a quick read that gave my book club a lot to talk about. While not everyone appreciated the obligatory Picoult twist, overall we felt the story was interesting and entertaining.

I was amazed by this book and the outcome.

Really liked this book. Compelling story of a mother that has a child, Anna, to save her child, Kate who has a rare leukemia. Very moving book. I look fwd to our discussion this wed.

I really liked this book as I do most of Jodi Picoult's books. She always manages to make you see an issue from both sides and make you question what you initially thought was right.

I could not put this book down. I didn't want to finish until I knew how it ended.

Every book I have read of Jodi's has been well worth the time spent. My Sisters Keeper is truly thought provoking.The love between the sisters runs deep as does the guilt of the parents.

We read the book and viewed the movie at our meeting. We all liked the book. The themes (including conceiving a designer baby to help another with a life-threatening illness) are thought provoking. Although the movie followed the general plot of the book, it didn't have the same depth. The characters weren't fully developed, which left it just mostly sad. More surprising, the ending was totally different -- more predictable, but kind of flat. I'd recommend reading the book and skipping the movie.

Very touching story.

I really enjoyed this book. It was very emotional, but also inspiring.

The book provoked discussion on several issues: 1) how the younger sister must have felt and 2) how parents who do this (and there are some) really feel about the child they've created specifically to be a donor. Very thought provoking...and disturbing at the same time.

Our club very much enjoyed this book. We found it to be engaging and well written. The multiple narratives keep the book from getting boring while showing the various perspectives. It also has a lot of great discussion material.

This book keeps you turning the pages, well written, great twist inspiring! Too bad the movie had to ruin the story!!!

Great discussion book - enjoy by everyone.

Definitely wouldn\\\'t skip this book…great Book Club selection that inspired deeply moving conversations that really helps members of the club get to know each other better. Very god choice.

Good book - lots of twists - not fond of the ending but can't think of any other way it should end.

great read, sad story