In a panoramic sweep of the years leading up to the First Reform Bill of 1832, George Eliot explores nearly every subject of concern to modern life: art, religion, science, politics, self, society, human relationships. Among her characters are some of the most remarkable portraits in English literature: Dorothea Brooke, the heroine, idealistic but naive; Rosamund Vincy, beautiful and egoistic; Edward Casaubon, the dry-as-dust scholar; Tertius Lydgate, the brilliant but morally flawed physician; the passionate artist, Will Ladislaw; and Fred Vincy and Mary Garth, childhood sweethearts whose charming courtship is one of the many humorous elements in the novel's comic vein.

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